The Neurophotometrics
Fiber Photometry System

Plug-and-Play Fiber Photometry

At Neurophotometrics, we’re not looking to sell you a bunch of parts. We don’t want you to spend unnecessary time building a system, which in our experience can take 3-6 months and still not produce a very polished user experience. Our system is fully functional as soon as it arrives (provided you’ve got the animals and they’re expressing the right indicators, of course).


Our system has three excitation wavelengths:

  • 470 nm for imaging of green calcium indicators (e.g. GCaMP)
  • 560 nm for imaging of red-shifted calcium indicators (e.g. RCaMP)
  • 415 nm for an interleaved isosbestic control to eliminate motion artifacts (i.e. calcium-independent signals)

Our system also comes with a CMOS camera and integrated image splitter to capture calcium signals.


Our system is fully compatible with Bonsai, a free and open source program. The data output takes the form of a .csv file, which you can then analyze however you’re most comfortable.

Fiber Optic Cannulae

We offer fiber optic cannulae (FOC) with black ceramic ferrules that have been optimized for fiber photometry with an 80% efficiency cutoff. Be sure to opt for a low autofluorescence fiber and match the numerical aperture (we can help with this).

FOC are $20/each, with discounts for bulk orders.
$18/each for 100+ FOC
$17/each for 200+ FOC
$15/each for 500+ FOC
Shipping is free for bulk FOC orders.
Add a ferrule jig for $20.

Onsite Training and Installations

The Neurophotometrics team is committed to providing a top-notch user experience. We want you able to start collecting data as fast as possible, which is why we offer onsite training and installation. Our fiber photometry system may be plug-and-play, but we can help to shorten the learning curve. Our scientists will travel to your lab and train your team over the course of a two-day installation workshop. Plus, the support doesn’t end when our team departs — we’re always available to help, from designing experiments and analysis pipelines to troubleshooting.

What Else Do You Need?

Patch Cords: We no longer manufacture patch cords in-house, but we strongly endorse those made by Doric Lenses.

Camera for Behavior Tracking: If you require behavior tracking for your experiments, you’ll need a camera. No need to break the bank on something fancy — we recommend ordering this one on Amazon.